A study on differentiation of extra-cardiac activity by Slit Slat collimation in Single Photon Emission Computed Tomography
Authors
Abstract:
Introduction: Myocardial perfusion SPECTby 99mTc-Sestamibi and 99mTc-Tetrofosmin radiopharmaceuticals usually presents a false significant increase in the radiotracer uptake in the inferior myocardium due to the uptake in organs such as liver, bowel, stomach and biliary system. The present study evaluated a suitable Slit angle for differentiating extra-cardiac activities by Slit Slat collimation. Methods: The Siemens E.CAM gamma camera equipped with a Low Energy High Resolution (LEHR) collimator was simulated with the Simulating Medical Imaging Nuclear Detectors (SIMIND) Monte Carlo program. Following the verification of the simulation, a Slit Slat collimator was simulated for SPECT imaging of a NURBS-based Cardiac Torso (NCAT) phantom with different Slit angels ranged from 0 to 30 degrees. The reconstructed images were qualitatively assessed with blinded observer method by three nuclear medicine specialists. Results:The improved differentiation of the bowel activity from the cardiac was obtained by a Slit-Slat collimator with the Slit angle of 7 degree. While for gastric activity differentiation an angle of 15 degree for the Slit was useful. Conclusion: The results showed that Slit Slat collimation with 7 and 15 Slit angle provide a suitable differentiation of the bowel and gastric activities from the cardia, respectively.
similar resources
Image Optimization in Single Photon Emission Computed Tomography by Hardware Modifications with Monte Carlo Simulation
Introduction: In Single Photon Emission Computed Tomography (SPECT), the projection data used for image reconstruction are distorted by several factors, including attenuation and scattering of gamma rays, collimator structure, data acquisition method, organ motion, and washout of radiopharmaceuticals. All these make reconstruction of a quantitative SPECT image very difficult. Simulation of a SP...
full textMonte Carlo Study of the Effect of Backscatter Materail Thickness on 99mTc Source Response in Single Photon Emission Computed Tomography
Introduction SPECT projections are contaminated by scatter radiation, resulting in reduced image contrast and quantitative errors. Backscatter constitutes a major part of the scatter contamination in lower energy windows. The current study is an evaluation of the effect of backscatter material on FWHM and image quality investigated by Monte Carlo simulation. Materials and Methods SIMIND program...
full textAttenuation correction in cardiac positron emission tomography and single-photon emission computed tomography.
Quantitation in cardiac positron emission tomography (PET) and single-photon emission computed tomography (SPECT) depends on being able to correct for several physical factors that tend to distort the data. One of the most important of these corrections is the correction for attenuation. For PET, cardiac attenuation correction is a reality, although certain problems remain to be solved. For SPE...
full textPositron emission tomography and single photon emission computed tomography.
Neuroimaging techniques have had a dramatic impact on the evaluation and treatment of patients with epilepsy. In order to take full advantage of their potential, it is important to place them in clinical and electrophysiological context and to understand their technical limitations. Positron emission tomography with 18F-2-deoxyglucose and single photon emission computed tomography can provide v...
full textSingle photon emission computed tomography tracer.
Single photon emission computed tomography (SPECT) is the state-of-the-art imaging modality in nuclear medicine despite the fact that only a few new SPECT tracers have become available in the past 20 years. Critical for the future success of SPECT is the design of new and specific tracers for the detection, localization, and staging of a disease and for monitoring therapy. The utility of SPECT ...
full textMy Resources
Journal title
volume 26 issue 1
pages 22- 29
publication date 2018-01-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023